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Antiplasmodial, β-haematin inhibition, antitrypanosomal and cytotoxic activity in vitro of novel 4-aminoquinoline 2-imidazolines

✍ Scribed by Musonda, Chitalu C.; Yardley, Vanessa; Carvalho de Souza, Renata C.; Ncokazi, Kanyile; Egan, Timothy J.; Chibale, Kelly

Book ID
120340153
Publisher
Royal Society of Chemistry
Year
2008
Tongue
English
Weight
150 KB
Volume
6
Category
Article
ISSN
1477-0520

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In vitro antiproliferative and cytotoxic
In vitro antiproliferative and cytotoxic activities of novel kojic acid derivatives: 5-benzyloxy-2-selenocyanatomethyl- and 5-methoxy-2-selenocyanatomethyl-4-pyranone
✍ Maria Fickova; Eliska Pravdova; Lars Rondhal; Michal Uher; Julius Brtko 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 226 KB

## Abstract Some kojic acid (KA) derivatives and selenium containing compounds possess antiproliferative properties. The present study tested novel selenocyanatomethyl derivatives of KA for growth inhibitory and LDH cytotoxic activities. Human skin carcinoma (A431) and human breast carcinoma (MCF7)