## Abstract We compared the frequency of clinical features of systemic lupus erythematosus (SLE) and determined survival in 113 patients with youngerβonset lupus (age β©Ύ < at clinical diagnosis) and 25 patients with olderβonset disease (age β©Ύ55 at diagnosis). The most striking difference was in the
Antiphospholipid syndrome modifies the clinical features of systemic lupus erythematosus
β Scribed by Harada, Masaru ;Mitsuyama, Keiichi ;Yoshida, Hiroshi ;Sakisaka, Shotaro ;Tokunaga, Yohko ;Sakamoto, Akiko ;Aiga, Moto ;Sasatomi, Kurumi ;Sakamoto, Masaharu ;Akashi, Hidetoshi ;Sata, Michio ;Tanikawa, Kyuichi
- Publisher
- Informa UK (Informa Healthcare)
- Year
- 1999
- Tongue
- English
- Weight
- 446 KB
- Volume
- 9
- Category
- Article
- ISSN
- 0169-1163
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## Abstract ## Objective To evaluate the prevalence, clinical associations, and outcome of antiphospholipid syndrome (APS) nephropathy in patients with systemic lupus erythematosus (SLE) and antiphospholipid antibodies (aPL) and in SLE patients without aPL. ## Methods Kidney biopsy specimens obt
Familial associations of the antiphospholipid antibody syndrome (APS) offer the opportunity to study genetic mechanisms of autoantibody production and disease, but are unusual. We identified a family, including identical twins and their mother, in which all members had systemic lupus erythematosus (