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Antiparasitic nitroimidazoles. 9. Synthesis of some 2-(4-dialkylaminomethylstyryl)- and 2-(4-amidinostyryl)-5-nitro-1-vinylimidazoles

✍ Scribed by Ross, William J.; Jamieson, William B.


Book ID
126434679
Publisher
American Chemical Society
Year
1975
Tongue
English
Weight
343 KB
Volume
18
Category
Article
ISSN
0022-2623

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A simple four-stage conversion of 2-1nethyl-4(5>nitroimidazole to 2-methyl-4(5)-nitr0['~N""]imidazole is reported. The method consists in N-nitration of the initial compound to ?-methyl-1,4-dinitroimidazole, treating the latter with ["Nlglycine and N-dealkylation of the obtained (~-rnethyl-4-nitro[~