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Antioxidant Activity of Graft Chitosan Derivatives

✍ Scribed by Tao Sun; Wenming Xie; Peixin Xu

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
123 KB
Volume
3
Category
Article
ISSN
1616-5187

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✦ Synopsis

Abstract

Graft chitosan derivatives (CMCTS‐g‐MAAS and CMCTS‐g‐AAS) were prepared by the graft copolymerization of methacrylic acid sodium (MAAS) and acrylic acid sodium (AAS) onto the etherification product of chitosan‐carboxymethyl chitosan (CMCTS). Their antioxidant activity was estimated as superoxide anion scavengers by chemiluminescence techniques. The derivatives with low grafting percentages have a relatively low 50% inhibition concentration (IC~50~), which could be related to the fact that they have different contents of hydroxyl and amino groups in the polymer chains.

Superoxide radical scavenging activity of CMCTS‐g‐MAAS.

magnified imageSuperoxide radical scavenging activity of CMCTS‐g‐MAAS.

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## Abstract Essential oils are known to possess antimicrobial and antioxidant activity while chitosan is a biocompatible polymer with antibacterial activity against a broad spectrum of bacteria. In this work, nanoparticles with both antioxidant and antibacterial properties were prepared by grafting