## Abstract Serum C3, C4, and total hemolytic complement (CH50) levels were measured for 21 children with systemic lupus erythematosus (SLE) and 81 first degree relatives. The mean serum C4 and CH50 levels of the 12 relatives with antinuclear antibodies (ANA) were depressed to levels equal to those
Antinuclear factor in systemic lupus erythematosus. A consideration of the immunofluorescent method of detecting antinuclear antibodies, with results obtained in a family study
β Scribed by John Holborow; Gerald D. Johnson
- Publisher
- John Wiley and Sons
- Year
- 1964
- Tongue
- English
- Weight
- 570 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0004-3591
No coin nor oath required. For personal study only.
β¦ Synopsis
An immunofluorescent technique used for demonstrating antinuclear factor is discussed and the possible influence of differences in method on A.N.F. findings in family studies already reported is considered. The incidence of serum antinuclear factor in first degree relatives of patients suffering from systemic lupus erythematosus was higher than in matched population controls; the difference was a small but a significant one.
Es discutite un technica immunofluorescente utilisate pro le demonstration del factor antinuclear. Le possible influentia de differentias in methodo super constatationes de factor antinuclear in previemente reportate studios familial es considerate. In consanguineos del prime grado de patientes suffrente de systemic lupus erythematose le incidentia del factor antinuclear in Ie sero esseva plus grande que in le appariate population de controlo. Iste differentia esseva micre sed significative.
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