Antinociceptive Effects in Normal and Diabetic Rats Exposed to 50
β Scribed by M. I. Kosar; T. Demir; A. Demirkazik; K. Deveci; E. Ozdemir; S. Gulturk
- Book ID
- 113076933
- Publisher
- Springer US
- Year
- 2012
- Tongue
- English
- Weight
- 736 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0090-2977
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Background Hyperlipidaemia has been suggested to contribute by proβapoptotic actions to the loss of Ξ²βcell mass, its secretory defects, and thereby impaired Ξ²βcell function in type 2 diabetes. Treatment of genetically diabetic rats and also type 2 diabetic patients with pioglitazone
The effects of synthetic rat C-peptide 1 and C-peptide 2 on plasma insulin and blood glucose concentrations in the rat were studied. Infusion of rat C-peptide (500 micrograms X h-1 X kg-1) diminished glucose induced increase of plasma insulin by 56% (15.2 +/- 0.9 versus 6.6 +/- 0.6 ng/ml, p less tha