Synthesis and Antimicrobial Activity of 6-Substituted 2-(5-Nitro-2-furyl)-1,3,4,9-tetraazafluorenes. -The title tetraazafluorenes (III) containing a nitrofuryl as well as an isatin fragment, easily synthesized by condensation of isatin with furohydrazide imide (II), possess activity against E. coli
Antimycotic activity of 6-R-2-(5-nitrofur-2-yl)-1,3,4,9-tetraazafluorenes
✍ Scribed by P. A. Pavlov; N. Yu. Basova; P. P. Pavlov
- Publisher
- Springer
- Year
- 1999
- Tongue
- English
- Weight
- 63 KB
- Volume
- 33
- Category
- Article
- ISSN
- 0091-150X
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📜 SIMILAR VOLUMES
In the chiral title compound, C 39 H 58 N 4 O 2 S 2 , the complete molecule is generated by crystallographic twofold symmetry, with one C atom lying on the rotation axis. The packing is established by van der Waals forces.
## Abstract For Abstract see ChemInform Abstract in Full Text.
The ring itself has a somewhat flattened twist-boat conformation. C-HÁ Á ÁO interactions join the molecules into a twodimensional network running parallel to the (101) plane.
## Abstract Stereoselective synthesis of 5‐[2‐(guanin‐9‐yl)‐ and 5‐[2‐(2‐aminopurin‐9‐yl)ethyl]‐2‐D‐ribo‐(1′,2′,3′,4′‐tetrahydroxybutyl)‐1,3‐dioxane, 2‐5, as potential prodrugs of penciclovir, has been accomplished in six steps from readily available 2,3,4,5‐tetra‐__O__‐acetyl‐__aldehydo__‐D‐ribose