One of the main problems in the culture of Chinese Hamster Ovary (CHO) cells continues to be the inability to maintain the viability of the cultures over an extended period of time. The rapid decline in viability at the end of the culture is exacerbated by the absence of serum. In trying to reduce t
Antimutagenic activities of naturally occurring polyamines in Chinese hamster ovary cells in vitro
โ Scribed by Dr. Renata Cozzi; Paolo Perticone; Roberta Bona; Stefania Polani; D. A. Casciano
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 450 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0893-6692
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The glycosylation patterns of recombinant therapeutic glycoproteins can be engineered by overexpression of glycosyltransferases in the host cells used for glycoprotein production. Most prior glycosylation engineering experiments have involved constitutive expression of cloned glycosyltransferases. H
## Abstract To determine if Chinese Hamster Ovary (CHO) cells in culture are able to metabolize steroids, CHO cells were incubated in defined medium with [^14^C]pregnenolone. As shown, [^14^C]pregnenolone is metabolized to progesterone and other ฮด^5^3ฮฒ steroids; this steroidogenic response is appre
A strong teratogen-6-aminonicotinamide (6-AN)-was tested for its ability to induce cytotoxicity and mutagenicity in Chinese hamster ovary (CHO) cells. Tests were performed in the presence and absence of a metabolic activation system (S-9 mix). Cytotoxicity was evaluated in CHO cells by the total pro
Stability of heterologous protein expression during production is critical for regulatory approval of vaccine and therapeutic products. Leishmania GP63, a zinc metalloproteinase that is a potential vaccine candidate, has been expressed on the surface of Chinese hamster ovary (CHO) cells. Flow cytome