Antimitochondrial antibody-negative primary biliary cirrhosis: a subset of primary biliary cirrhosis
โ Scribed by Bin Liu; Xu Hua Shi; Feng Chun Zhang; Wen Zhang; Li Xia Gao
- Book ID
- 111237819
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 116 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0106-9543
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๐ SIMILAR VOLUMES
In our previous work, including analysis of more than 10,000 sera from control patients and patients with a variety of liver diseases, we have demonstrated that with the use of recombinant autoantigens, antimitochondrial autoantibodies (AMAs) are only found in primary biliary cirrhosis (PBC) and tha
## Anti -mitochondrial antibodies (AMAs) have long been recognized as a serological hallmark of primary biliary cirrhosis (PBC). Although high titers of immunoglobulin (Ig)A AMAs are found in bile, saliva, and urine of patients, a pathogenic role for this antibody has remained elusive. Functional