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Antimalarials. 2. 2,6-Bis(aryl)-4-pyridinemethanols

โœ Scribed by Blumbergs, P.; LaMontagne, M. P.; Markovac, A.; Moehring, J. G.; Ash, A. B.; Stevens, C. L.


Book ID
126897620
Publisher
American Chemical Society
Year
1972
Tongue
English
Weight
549 KB
Volume
15
Category
Article
ISSN
0022-2623

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โœ O. J. Bouwsma; J. T. Stewart; J. J. Vallner ๐Ÿ“‚ Article ๐Ÿ“… 1979 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 437 KB

Binding of the antimalarial alpha-dibutylaminomethyl-2,6-bis(trifluoromethylphenyl)-4-pyridinemethanol with human serum albumin was studied using difference spectroscopy, fluorescence quenching, and equilibrium dialysis. Results indicated that the number of high affinity binding sites of the drug on