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Antimalarials. 7. 2,8-Bis(trifluoromethyl)-4-quinolinemethanols

✍ Scribed by Blumbergs, Peter; Ao, Meng-Sheng; LaMontagne, Maurice P.; Markovac, Anica; Novotny, Jaroslav; Collins, Carol H.; Starks, Fred W.


Book ID
127380031
Publisher
American Chemical Society
Year
1975
Tongue
English
Weight
699 KB
Volume
18
Category
Article
ISSN
0022-2623

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14C-labeled antimalarials. I. Synthesis
✍ William H. Yanko; George F. Deebel πŸ“‚ Article πŸ“… 1980 πŸ› John Wiley and Sons 🌐 French βš– 291 KB

## Abstract Erythro‐ and threo‐ isomers of α‐(2‐piperidyl)‐2,8‐bis‐(triflucoromethyl)‐4‐quinolinemethanol‐α‐^14^C hydrochloride and methanesulfonate were prepared from labeled carbon dioxide for metabolic and pharmacological studies. Intermediates were 2,8‐bis(trifluoromethyl) cinchoninic‐carboxy‐^