Antimalarial Potential of Xestoquinone (I), a Protein Kinase Inhibitor Isolated from a Vanuatu Marine Sponge Xestospongia sp.

Synthesis of Sphingosine Relatives, XVII

Synthesis of Sphingosine Relatives, XVIII!. Synthesis of Penazetidine A, an Alkaloid Inhibitor of Protein Kinase C Isolated from the Marine Sponge Penares sollasi

✍ Yajima, Arata ;Takikawa, Hirosato ;Mori, Kenji 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 819 KB

## Abstract Two stereoisomers of penazetidine A (1a), the azetidine alkaloid isolated from the Indo‐Pacific marine sponge __Penares sollasi__, were synthesized by starting from (__S__)‐serine and (__R__)‐or (__S__)‐citronellol. The natural penazetidine A must be either (2__S__,3__R__,4__S__,12′__R_