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Antihypertensive mechanism of action of ketanserin and some ketanserin analogues in the spontaneously hypertensive rat

โœ Scribed by Anders Pettersson; Kathryn Gradin; Thomas Hedner; Bengt Persson


Book ID
112340872
Publisher
Springer-Verlag
Year
1985
Tongue
English
Weight
437 KB
Volume
329
Category
Article
ISSN
0028-1298

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Ketanserin, a serotonin antagonist, is effective in lowering portal pressure in a rat model of portal hypertension. As ketanserin has al-adrenoceptor-blocking properties in addition to its serotonin-blocking effects, we sought to define further the mechanism of ketanserin's portal pressure-lowering