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Antihormonal agents. Part 2: HPLC of ZK 98734 and its metabolites and ZK 98299

โœ Scribed by Matlin, S. A. ;Wu, Z. Y.


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
165 KB
Volume
10
Category
Article
ISSN
0935-6304

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โœฆ Synopsis


Proceduresaredescribed forthe reverse phase HPLCanalysisof the antihorrnonal steroid ZK 98734 and two of its metabolites. Conditions are developed for the HPLC of the pure drug substance and for following its pharrnacokinetics and metabolism. Analysis conditions are also reported for the antiprogestin ZK 98299.

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Antihormonal agents. Part 1: HPLC of RU
โœ Matlin, S. A. ;Abderabbani, N. ๐Ÿ“‚ Article ๐Ÿ“… 1987 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 233 KB

Procedures are described for the TLC and reverse phase HPLC analysis of the antihormonal steroid RU 38486 and its metabolites. Conditions are developed for the HPLC of the pure drug substance and a tablet formulation, and also for following its pharmacokinetics and metabolism.