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Antigenicity of cortical bone allografts in dogs and effect of ethylene oxide-sterilization

✍ Scribed by M Tshamala; E Cox; H De Cock; B.M Goddeeris; D Mattheeuws


Book ID
117336913
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
182 KB
Volume
69
Category
Article
ISSN
0165-2427

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Freeze-dried bone allograft (FDBA) which either had or had not been sterilized by exposure to ethylene oxide (EtO) prior to lyophilization was obtained from two commercial sources. EtO-sterilized FDBA was reexposed to EtO as a positive control. Gas chromatograph assays revealed that three out of fou

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The effects of preservation and sterilization on the structural properties of cortical bone were investigated. Specimens of cortical bone from rat tibiae were frozen (-70Β°C for 28 days), freeze-dried, irradiated (1, 5, 25 and 50 kGy) or autoclaved (at 134Β°C for 3 or 5 rain), and examined by scanning