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Antigen receptor-initiated signals for B Cell development and selection

✍ Scribed by John G. Monroe


Book ID
105608319
Publisher
Springer-Verlag
Year
1998
Tongue
English
Weight
968 KB
Volume
17
Category
Article
ISSN
0257-277X

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The binding of antigens to the B cell antigen receptor (BCR) results in the initiation of signaling cascades and the internalization of the antigens for processing and presentation. Recent studies indicate that antigen binding destabilizes the BCR as a mechanism to down-regulate B cell responses. Tw