Most antibody panels proposed for flow cytometric immunophenotyping of non-Hodgkin's lymphomas and chronic lymphoid leukemias include anti-CD20 and FMC7 antibodies. As in our experience, reactivity of B-cells with these antibodies seemed to be correlated, we evaluated whether the simultaneous use of
β¦ LIBER β¦
Antigen-presenting function of B-cell precursor malignant cells can be modulated by crosslinking of CD40
β Scribed by A. A. Cardoso; J. L. Schultze; D. Provan; G. J. Freeman; M. Seamon; J. G. Gribben; L. M. Nadler
- Book ID
- 112784536
- Publisher
- Springer-Verlag
- Year
- 1995
- Tongue
- English
- Weight
- 168 KB
- Volume
- 121
- Category
- Article
- ISSN
- 1432-1335
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## Anti -CD3 Ψ anti-B-cell antigen bispecific monoclonal antibodies (bsAbs) can redirect T-cell-mediated lysis toward malignant B cells. Clinical trials with CD3-based bsAbs have shown toxicity in patients which is likely related to nonspecific T-cell activation and targeting. Our current studies