𝔖 Bobbio Scriptorium
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Antigen presentation: Peptides and proteins scramble for the exit

✍ Scribed by Paul J Lehner; Eric W Hewitt; Karin Römisch


Book ID
114317944
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
331 KB
Volume
10
Category
Article
ISSN
0960-9822

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Processing of peptides for antigen presentation is catalyzed by antigen-trimming enzymes, including the proteasome and leucine aminopeptidase. Oxidative stress suppresses proteasome function. We hypothesized that in liver cells, processing of antigenic peptides is altered by ethanol metabolism. To a