Antigen presentation by liposomes: Inhibition with antibodies
β Scribed by Peter Walden; Zoltan A. Nagy; Jan Klein
- Book ID
- 102160810
- Publisher
- John Wiley and Sons
- Year
- 1986
- Tongue
- English
- Weight
- 386 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0014-2980
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Anti-cytochrome c and anti-myoglobin antibodies were assayed by use of immunoliposomes coupled with the antigens. Addition of complement under the existence of the antigen-antibody complex on the surface of the liposome caused lysis of the liposomes, which was proportional to the amount of the antig
Using the earlier established liposome system for antigen presentation, in which liposomes bearing major histocompatibility complex (MHC)-class II molecules inserted into and protein antigen covalently linked to the membrane were found to be sufficient for an antigen-specific and MHC-restricted acti