𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Antigen presentation and tumor cytotoxicity by interferon-γ-treated microglial cells

✍ Scribed by Karl Frei; Christine Siepl; Peter Groscurth; Stefan Bodmer; Cornelia Schwerdel; Adriano Fontana


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
967 KB
Volume
17
Category
Article
ISSN
0014-2980

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Antigen presentation by MHC class I and
✍ Klaus Früh; Young Yang 📂 Article 📅 1999 🏛 Elsevier Science 🌐 English ⚖ 114 KB

Antigen processing by MHC class I molecules begins with the generation of peptides by proteolytic breakdown of proteins. IFN-γ upregulates gene expression of several proteasomal subunits as well as the proteasome regulator PA28; this implicated their role in antigen degradation. Crystallographic, mu

Presentation of prostate tumor antigens
✍ Tjoa, Benjamin; Boynton, Alton; Kenny, Gerald; Ragde, Haakon; Misrock, S. Leslie 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 475 KB 👁 2 views

Dendritic cells (DCs) are "professional" antigen-presenting cells capable of stimulating T-cell proliferation and cytotoxicity when loaded with and presenting specific antigens, including tumor antigens. We demonstrated the stimulation of an autologous cytotoxic T-cell response elicited by DC loaded

Presentation of native TROP-2 tumor anti
✍ Giorgio Mangino; Maria Grazia Capri; Vincenzo Barnaba; Saverio Alberti 📂 Article 📅 2002 🏛 John Wiley and Sons 🌐 French ⚖ 189 KB 👁 1 views

Professional antigen-presenting cells (APC), e.g. dendritic cells, express immuno-proteasome components and process proteins for MHC presentation differently from non-immune cells. Thus, they induce reactivities against sets of peptides that do not overlap with those generated by non-professional AP

Differential presentation of tumor antig
✍ Gerhard Held; Frank Neumann; Christine Sturm; Lars Kaestner; Nina Dauth; Diederi 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 French ⚖ 311 KB

## Abstract SSX2 is a member of the family of cancer/testis antigens. The SSX2 derived peptide SSX2~103–111~ has been shown to be presented to cytotoxic T‐lymphocytes (CTL) by Major‐Histocompatibility (MHC) Class‐I complexes after endogenous processing, more precisely by the allele HLA‐A\*0201. The