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Antigen-Binding Mutants of Mouse Myeloma Cells

✍ Scribed by W. D. Cook and M. D. Scharff


Book ID
123654642
Publisher
National Academy of Sciences
Year
1977
Tongue
English
Weight
897 KB
Volume
74
Category
Article
ISSN
0027-8424

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One useful approach for the study of cell surface antigen biosynthesis and regulation is to isolate cell lines that fail to express the antigen of interest. Complementation analysis between mutant cell lines allows the detection of the steps required for expression of the molecule on the cell surfac