## Abstract 5‐Substituted (amine, alkyl, aryl, heterocyclic) 4‐(1,3,4‐thiadiazol‐2‐yl)benzene‐1,3‐ diols were synthesized, and their antifungal properties were examined. The compounds were obtained by the one‐pot reaction of sulfinylbis((2,4‐dihydroxyphenyl)methanethione) with hydrazides or thiosem
Antifungal agents I. 5 -substituted-3–(trichloromethyl) -1,2,4-thiadiazoles
✍ Scribed by V. L. Narayanan; Jack Bernstein; J. Williams
- Publisher
- John Wiley and Sons
- Year
- 1966
- Tongue
- English
- Weight
- 159 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0022-3549
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## Abstract magnified image One‐stage synthesis of 5‐substituted (alkyl, aryl, heteroaryl, arylalkyl, heteroalkyl, alkoxy‐, aryloxy)‐2‐(2,4‐dihydroxyphenyl)‐1,3,4‐thiadiazoles is described. The compounds were prepared by the reaction of sulfinyl‐bis(2,4‐dihydroxythiobenzoyl) (STB) with hydrazides
hydrates could be air milled, the author proceeded to pnpare suspensions with air-milled hydrate to see if crystal growth still oe curted. Work was done with I-hydrate, because at that time development work on 11 had been discontinued. A 2.5% suspension of air-milled I-hydrate was made (Table ) and