Antiestrogen interaction with estrogen receptors and additional antiestrogen binding sites in human breast cancer MCF-7 cells
✍ Scribed by Mee Ryung Ahn; Yhun Yhong Sheen
- Publisher
- Springer
- Year
- 1997
- Tongue
- English
- Weight
- 603 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0253-6269
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## Abstract We show that flavonoids positively regulate type‐II estrogen‐binding site (type‐ll EBS) levels both in MCF‐7 (ER‐positive) and in MDA‐MB231 (ER‐negative) breast‐cancer cells. Type‐ll EBS were measured by a whole‐cell assay at 4°C for 2.5 hr using [^3^H]‐estradiol as tracer. In both cell
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