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Quercetin inhibits the growth of a multidrug-resistant estrogen-receptor-negative MCF-7 human breast-cancer cell line expressing type II estrogen-binding sites

✍ Scribed by G. Scambia; F. O. Ranelletti; P. Benedetti Panici; M. Piantelli; G. Bonanno; R. Vincenzo; G. Ferrandina; L. Pierelli; A. Capelli; S. Mancuso

Publisher
Springer
Year
1991
Tongue
English
Weight
478 KB
Volume
28
Category
Article
ISSN
0344-5704

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📜 SIMILAR VOLUMES

Quercetin induces type-II estrogen-bindi
Quercetin induces type-II estrogen-binding sites in estrogen-receptor-negative (MDA-MB231) and estrogen-receptor-positive (MCF-7) human breast-cancer cell lines
✍ G. Scambia; S. Mancuso; P. Benedetti Panici; R. De Vincenzo; G. Ferrandina; G. B 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 French ⚖ 536 KB

## Abstract We show that flavonoids positively regulate type‐II estrogen‐binding site (type‐ll EBS) levels both in MCF‐7 (ER‐positive) and in MDA‐MB231 (ER‐negative) breast‐cancer cells. Type‐ll EBS were measured by a whole‐cell assay at 4°C for 2.5 hr using [^3^H]‐estradiol as tracer. In both cell