𝔖 Bobbio Scriptorium
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Antidotes against venomous animals: State of the art and prospectives

✍ Scribed by G.P. Espino-Solis; L. Riaño-Umbarila; B. Becerril; L.D. Possani


Publisher
Elsevier
Year
2009
Tongue
English
Weight
745 KB
Volume
72
Category
Article
ISSN
1874-3919

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✦ Synopsis


This communication revises the state of the art concerning antivenoms against snakes, spiders and scorpions. An overview of the historical facts that preceded the therapeutic use of antibodies is mentioned. A brief list of the major protein components of these venomous animals is revised with a short discussion of what is known on the proteomic analysis of their venoms, but the emphasis is placed on the type of antivenoms available commercially, including pertinent literature and addresses of the companies that prepare these antivenoms. The final section revises and discusses current research on the field and new potential applications that are being developed geared at obtaining new therapeutic antibodies or fragments of antibodies for neutralization of toxic components of venomous animals.


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