Introduction: State of the art in transgenic animals in mutation research

✍ Scribed by Nancy J. Gorelick; Kenneth R. Tindall; Barry W. Glickman

• Publisher: John Wiley and Sons
• Year: 1996
• Tongue: English
• Weight: 406 KB
• Volume: 28
• Category: Article
• ISSN: 0893-6692
• DOI: 10.1002/(sici)1098-2280(1996)28:4<295::aid-em1>3.0.co;2-b

✦ Synopsis

A satellite meeting to the 1996 Annual Meeting of the Environmental Mutagen Society was held at Dunsmuir Lodge on Vancouver Island, British Columbia, Canada, to discuss studies involving the application of transgenic animals in mutation research. As organizers, we envisioned a relatively small meeting with a Gordon conference-style atmosphere intended to foster communication and discussion. In the end, the 102 international participants representing academia, industry, and several federal governments engaged in spirited discussions between formal presentations and short presentations from selected abstracts.

The scientific program was designed to achieve two distinct goals. First, we hoped to provide researchers with experimental and technical insights regarding the use of in vivo transgenic mutation assay systems. Second, we solicited a series of research presentations designed to provide a "state-of-the-art" understanding of current in vivo mutagenesis studies. Discussions of data generated to date in transgenic mutation assays were extended to discuss potential applications for the use of these systems in product safety evaluations. An overview of the meeting is available [Gorelick et al., 19961. This special issue of Environmental and Molecular Mu tagenesis includes complete research reports that highlight some of the topics discussed at the Satellite Meeting.