𝔖 Bobbio Scriptorium
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Antidote studies of vinorelbine-induced skin ulceration in the mouse

✍ Scribed by Robert T. Dorr, Kristi L. Bool

Book ID
120776421
Publisher
Springer
Year
1995
Tongue
English
Weight
300 KB
Volume
36
Category
Article
ISSN
0344-5704

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The highly vesicant nature of the alkylating anticancer agent mechlorethamine (HN2, or nitrogen mustard) requires careful i.v. technique during its administration. Skin toxicity due to HN2 extravasation is severe and typically prolonged over several months. Mouse skin toxicity studies were carried o