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Antidepressant activity of some Hypericum reflexum L. fil. extracts in the forced swimming test in mice

✍ Scribed by C.C. Sánchez-Mateo; C.X. Bonkanka; B. Prado; R.M. Rabanal

Book ID
116643510
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
186 KB
Volume
112
Category
Article
ISSN
0378-8741

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The influence of naloxone on the effects of several antidepressant drugs, atropine and caffeine was studied in the forced swimming test in mice. Naloxone itself has no effect in this test, but significantly reduces that of two tricyclic antidepressants, clomipramine (20 and 30 mg/kg) and desipramine