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Forced swimming test in mice: a review of antidepressant activity

✍ Scribed by Benoit Petit-Demouliere; Franck Chenu; Michel Bourin


Publisher
Springer
Year
2004
Tongue
English
Weight
163 KB
Volume
177
Category
Article
ISSN
0033-3158

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The influence of naloxone on the effects of several antidepressant drugs, atropine and caffeine was studied in the forced swimming test in mice. Naloxone itself has no effect in this test, but significantly reduces that of two tricyclic antidepressants, clomipramine (20 and 30 mg/kg) and desipramine