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Anticytokinin activity of 4-substituted triazolo[4,5-d]pyrimidines and 4-substituted pyrazolo[3,4-d]pyrimidines

✍ Scribed by V. Alexieva; I. Sergiev; E. Karanov; E. Golovinsky; E. Stanoeva; M. Haimova; G. Petrov

Publisher: Springer
Year: 1994
Tongue: English
Weight: 527 KB
Volume: 13
Category: Article
ISSN: 0721-7595
DOI: 10.1007/bf00196375

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✦ Synopsis

The synthesis and physiological activity of some novel 4-substituted triazolo [4,5-d]pyrimidines and 4-substituted pyrazolo [3,4-d]pyrimidines are described. Most of the compounds possessed high anticytokinin activity towards purine (benzyladenine) and phenylurea (4-PU-30) type cytokinins. 1-Benzyl-4-ethoxycarbonylpiperazinyl-1H-1,2,3-triazolo [4,5-d]pyrimidine almost completely removed cytokinin stimulated effects betacyanin synthesis in Amaranthus caudatus cotyledons; growth of radish cotyledons and retention of chlorophyll in leaf explants. Some chemical structurephysiological activity relationships have been established.

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