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Anticryptosporidial Potential of Alpha-1-Antitrypsin

โœ Scribed by JOHN R. FORNEY; SHIGUANG YANG; AND MARK C. HEALEY


Book ID
110105584
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
141 KB
Volume
43
Category
Article
ISSN
1066-5234

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A second case of Pi null alpha-1-antitrypsin (AA) deficiency is described. In fact, the serum's subject contains 5 mug of AA per millilitre. With radiolabelled specific antibodies, it is possible to describe the Pi phenotype associated to this deficiency. The pattern which is obtained is like the or

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Alpha-1-antitrypsin Pi phenotyping was performed by thin-layer isoelectric focusing on samples from 1653 healthy white blood donors. The variants were confirmed by the acid-starch gel technique and crossed immunoelectrophoresis, with complete agreement between the two methods. The allele frequencies