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Anticonvulsant effect of N-ethylcarboxamidoadenosine against kainic acid-induced behavioral seizures in the rat prepiriform cortex

✍ Scribed by Zhang, Ge; Franklin, Paul H.; Murray, Thomas F.

Book ID
122803585
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
321 KB
Volume
114
Category
Article
ISSN
0304-3940

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## Abstract Kainic acid (KA)‐induced status epilepticus (SE) is a well‐characterized model of excitotoxic neuronal injury. Excitotoxicity results from activation of specific glutamate receptors, with resultant elevation of intracellular Ca^2+^. The CA1 and CA3 subregions of the hippocampus are espe