The ether extract 18312-J of Ricinus communis seed (600 mg/kg and 1.2 g/kg) administered subcutaneously to rats possessed significant anticonceptive activity. The extract demonstrated an oestrogenic effect in immature ovariectomized rats and mice and was devoid of any antioestrogenic property. Furth
Anticonceptive and estrogenic effects of a seed extract of Ricinus communis var. minor
โ Scribed by Okwuasaba, F.K.; Osunkwo, U.A.; Ekwenchi, M.M.; Ekpenyong, K.I.; Onwukeme, K.E.; Olayinka, A.O.; Uguru, M.O.; Das, S.C.
- Book ID
- 122540886
- Publisher
- Elsevier Science
- Year
- 1991
- Tongue
- English
- Weight
- 517 KB
- Volume
- 34
- Category
- Article
- ISSN
- 0378-8741
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RICOM-1013-J (Ricinus communis var minor) administered orally once to each of 12 women volunteers at a dose of 2.5-2.7 g per 8 months, protected against pregnancy over a period of 7-8 months of study. A study of the effect of a contraceptive dose (20 mg/kg) on metabolic parameters in rat (food and w
The seeds of Ricinus communis Linn, RICOM-1013-J, administered as a single oral dose of 2.3-2.5 g once per 12 months protected against pregnancy in 50 women volunteers for a period of one year. The antifertility and contraceptive efficacy of the seed was demonstrated in this study. Clinical observat
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