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Anticandidal activity of pyrimidine-peptide conjugates

✍ Scribed by Ti, Jen-Shing; Steinfeld, Alvin S.; Naider, Fred; Gulumoglu, Ali; Lewis, Sam V.; Becker, Jeffrey M.

Book ID
120510031
Publisher
American Chemical Society
Year
1980
Tongue
English
Weight
787 KB
Volume
23
Category
Article
ISSN
0022-2623

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A series of carboxymethylpullulan (CMPul)-doxorubicin (DXR) conjugates bound by peptide spacers of different compositions and lengths were prepared and evaluated for their in vivo antitumor effects. Systematic study of the peptide spacers indicated that CMPul-DXR conjugates bound via appropriate dip