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Anticancer drugs: Two for one

✍ Scribed by Seton-Rogers, Sarah

Book ID
109950819
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
216 KB
Volume
8
Category
Article
ISSN
1474-1776

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A novel polymeric conjugate carrying two
A novel polymeric conjugate carrying two different anticancer drugs
✍ Song, Soo-Chang; Lee, Chong Ok; Sohn, Youn Soo πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 65 KB

Two different antitumour chemotherapeutic agents, doxorubicin and (dach)platinum(II) complex (dach = trans(AE)-1,2-diaminocyclohexane) were introduced into poly(organophosphazene) using L-glutamic acid as a spacer. The resultant polymeric conjugates exhibited high in vivo antitumour activity which i