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Antibody to the inositol trisphosphate receptor blocks thimerosalenhanced Ca2+-induced Ca2+ release and Ca2+ oscillations in hamster eggs

✍ Scribed by Shun-ichi Miyazaki; Hideki Shirakawa; Ken Nakada; Yoshiko Honda; Michisuke Yuzaki; Shinji Nakade; Katsuhiko Mikoshiba

Book ID
115926765
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
522 KB
Volume
309
Category
Article
ISSN
0014-5793

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## Abstract The initiation of normal embryo development depends on the completion of all events of egg activation. In all species to date, egg activation requires an increase(s) in the intracellular concentration of calcium ([Ca^2+^]~i~), which is almost entirely mediated by inositol 1,4,5‐trisphos