✦ LIBER ✦

Antibody response to the immediate early protein of cytomegalovirus in renal transplant recipients

✍ Scribed by Kimiyasu Shiraki; Michio Ishibashi; Toshiomi Okuno; Koichi Yamanishi; Michiaki Takahashi; Kazuko Tanaka; Koichi Baba; Hyakuji Yabuuchi; Yukito Kokado; Siro Takahara; Takao Sonoda

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 617 KB
Volume: 34
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890340413

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The antibody response to the immediate early protein (IEP) of cytomegalovirus (CMV) was examined in seven renal transplant recipients during CMV reactivation and associated clinical abnormalities. Three cases with antibody increase to the IEP in the week after CMV isolation had no CMV‐induced disease. The four patients without antibody increase exhibited laboratory abnormalities and three of them had renal dysfunction. In this small number of patients, the antibody response to the IEP in the week after isolation of CMV was associated with absence of abnormal clinical laboratory findings including renal function, and the prognosis was good for graft function in renal transplant recipients with CMV reactivation.

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