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Antibodies to synthetic peptides from the preS1 region of the hepatitis B virus (HBV) envelope (env) protein are virus-neutralizing and protective

โœ Scribed by A. Robert Neurath; Belinda Seto; Nathan Strick


Book ID
119150502
Publisher
Elsevier Science
Year
1989
Tongue
English
Weight
257 KB
Volume
7
Category
Article
ISSN
0264-410X

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Protective effect of a synthetic peptide
โœ Dr. Emilio A. Emini; Vivian Larson; Ronald W. Ellis; William J. Miller; Robert J ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 461 KB

A peptide was synthesized containing the entire 55 amino acid residue sequence of the hepatitis B virus (HBV) surface antigen preS2 region (ad subtype). The unconjugated peptide was inoculated into four chimpanzees. Following multiple injections, all of the animals developed specific antipeptide ant

Antibodies to translation products of th
โœ Iku Ise; Fumio Tsuda; Shinobu Aihara; Atsuhiko Machida; Emiko Takai; Hideaki Miy ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 611 KB

Sera from 11 patients with fulminant hepatitis B were tested for antibodies to translation products of the pre-S1 and pre-S2 regions of hepatitis B virus of IgM, IgA and IgG classes, as well as of IgA1, IgA2 and SIgA, with solid-phase enzyme immunoassays using native viral polypeptides. Antibodies t