Antibodies to phospholipids in experimental nocardiosis
β Scribed by A. K. Trana; S. C. Sehgal; G. K. Khuller
- Book ID
- 104754232
- Publisher
- Springer Netherlands
- Year
- 1978
- Tongue
- English
- Weight
- 307 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0003-6072
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β¦ Synopsis
Live Nocardia asteroides injected intraperitoneally into guinea pigs produced antibodies to phospholipids of Nocardia whereas antibodies were not detected in animals injected with heat-killed N. asteroides. The antibody titer was found to be related with the degree of infection; a significant decrease was noted after sulfadiazine treatment suggesting that antibodies were produced in response to an increasing bacterial load that occurred as the infection progressed.
π SIMILAR VOLUMES
Polyclonal and monoclonal antibodies to liposomes having various phospholipid compositions have been produced. Binding of the anti-lipid bilayer antibodies is influenced both by the chemical composition and the physical state of the liposomal lipids. The antibodies to liposomes have a 'subsite' in t