✦ LIBER ✦

Antibodies to hepatitis C virus in uremic patients on continuous ambulatory peritoneal dialysis

✍ Scribed by Yee-Yung Ng; Shou-Dong Lee; Shiao-Chi Wu; Wu-Chang Yang; Shoou-Shan Chiang; Tung-Po Huang

Publisher: John Wiley and Sons
Year: 1991
Tongue: English
Weight: 373 KB
Volume: 35
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890350411

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

The prevalence of antibody to hepatitis C virus (anti‐HCV) among 101 uremic patients receiving continuous ambulatory peritoneal dialysis (CAPD) was evaluated using a synthetic peptidebased HCV antibodies enzyme immunoassay. Thirty (29.7%) were found anti‐HCV positive. This is significantly higher than 500 unselected paid blood donors (4.2%, P < 0.0001). Among CAPD patients, anti‐HCV positivity was found more frequently in patients who had received frequent and longer duration of hemodialysis previously (40.4% vs. 20.4%, P < 0.05). These findings suggest that hemodialysis patients have a higher risk of HCV infection. At present, CAPD may be a suitable way to reduce the incidence of HCV infection in uremic patients.

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