## Abstract Antibodies to Epstein—Barr viral (EBV) antigens were studied in 12 patients with early (less than 6 weeks) rheumatoid arthritis (RA) and compared to controls. Geometric mean antibody titers to viral capsid antigen, early antigens, and Epstein—Barr‐associated nuclear antigen (EBNA) were
Antibodies to Epstein-Barr virus associated antigens in Pima Indians with and without rheumatoid arthritis
✍ Scribed by S. F. Slovin; T. T. Kuberski; D. A. Carson; M. A. Catalano; E. M. Reitz; J. H. Vaughan
- Publisher
- Springer
- Year
- 1983
- Tongue
- English
- Weight
- 359 KB
- Volume
- 3
- Category
- Article
- ISSN
- 0172-8172
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The incidence of antibodies to Epstein-Barr nucleair antigen type 2 (EBNA-2) was determined in sera from rheumatoid arthritis (RA) patients and control subjects, by protein immunoblotting. Sixty-eight percent of the RA patients and 48% of the controls possessed anti-EBNA-2 antibodies. The titer of a
Pannus extracts and/or cells and tissues from rheumatoid arthritis (RA) patients and controls were tested for the presence of RA-associated nuclear antigen (RANA), anti-RANA, Epstein-Barr virus (EBV)-specific antigens, and EBV genomes. Using our present rather insensitive methods, RANA was rarely de
## Abstract Antibody titers to Epstein‐Barr virus (EBV)‐specific antigens of 19 patients with hairy‐cell leukemia (HCL) were markedly elevated. All patients showed high titers of IgG anti‐viral capsid antigen (VCA) reactivity equal to or greater than 320 (reciprocal titer). The anti‐VCA reciprocal
## Abstract Titration of anti‐complementary human sera may yield false negative or prozone reactions in anti‐complement immunofluorescence (ACIF) tests for antibodies to Epstein‐Barr virus‐associated nuclear antigen (EBNA) when the human complement (C') is added to the serum dilutions prior to char
## Abstract Antibody reactivity to Epstein‐Barr virus (EBV)‐associated nuclear antigen (EBNA) was investigated by means of the anticomplement immunofluorescence technique on sera from patients with Hodgkin's disease (HD) and from appropriate controls. Antibody levels to other EBV‐determined antigen