Pharmacokinetics and biodistribution of
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Surinder K Batra; Maneesh Jain; Uwe A Wittel; Subhash C Chauhan; David Colcher
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Article
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2002
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Elsevier Science
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English
⚖ 70 KB
The engineering of monoclonal antibodies has created a new generation of pharmaceuticals with the desired pharmacokinetics and biodistribution properties. For radioimmunotherapy and radioscintigraphy, optimum tumor targeting can be achieved using engineered constructs that provide high antigen affin