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Antibiotics produced by Streptomyces VI. Pentafungin, a new antifungal antibiotic

✍ Scribed by J. Bérdy; I. Horváth


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
281 KB
Volume
5
Category
Article
ISSN
0233-111X

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✦ Synopsis


A Xtreptomyces strain, L23, isolated in our laboratories, produces a new antibiotic. This paper describes the characteristics of the strain, the method of fermentation and the preparation of the active substance in a crystalline form, and its chemical and biological properties.

Experimental

The production of the antibiot)ic substance was carried out on a reciprocal shaker (300 r.p.m., 2 em diameter), and in pilot-plant fermentors (stirring at 220 r.p.m., aeration: one litre per litre of broth) a t 28 "C. For the estimation of antibiotic the agar-diffusion method was used with Candida albicans, in a potato-extract glucose agar medium containing 3 % of potassium chlorida (HORVATH and KOCZKA 1964).


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Antibiotic NRC-501, a new antibiotic pro
✍ Prof. Dr. A. A. Abou-Zeid; M. M. Abd El-Hamid; Y. M. Shehata 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 525 KB

## Abstract A new antibiotic NRC‐501 was ioslated from the fermentation broth of __Streptomyces spec__. NRC‐501. Physical, chemical, and biological characteristics of the antibiotic were studied.