Antibacterial activities of a few prepared derivatives of oleanolic acid and of other natural triterpenic compounds

✍ Scribed by Fayçal Hichri; Hichem Ben Jannet; Jihen Cheriaa; Samir Jegham; Zine Mighri

• Publisher: Elsevier Science
• Year: 2003
• Tongue: English
• Weight: 304 KB
• Volume: 6
• Category: Article
• ISSN: 1631-0748
• DOI: 10.1016/s1631-0748(03)00066-3

✦ Synopsis

Oxidizing, phosphorus, ester and amide derivatives of oleanolic acid 1 have been prepared. The antibacterial activity of compound 1, isolated from the fruit barks of Periploca laevigata (Asclepiadaceae), and its derivatives have been tested using Tween-80 as complex agent to form a water-soluble triterpenes. The same activity of maslinic acid acetate 2, b-amyrin 3, and its acetylated derivative 3a (Fig. 1), isolated from the same source as that of oleanolic acid 1, have also been investigated.