Anti-Ulcer effect of FK 506, immunosuppressive agent, in rats
β Scribed by Akira Zeniya; Michiro Otaka; Toshiyuki Kuwabara; Shusel Fujimori; Setsuya Otani; Osamu Masamune
- Publisher
- Springer Japan
- Year
- 1994
- Tongue
- English
- Weight
- 114 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0944-1174
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π SIMILAR VOLUMES
The distribution kinetics of a novel potent immunosuppressant, FK-506 (FK) has been studied in comparison with cyclosporin A (CyA) both in vivo and in vitro using blood specimens. The infusion studies on FK, 5.0mg kg-1 through the portal and femoral veins showed that the mean hepatic extraction rati
We investigated the effect of an immunosuppressant FK-506 on histological change of islets, the onset of diabetes, and the change of spleen cell subsets in female non-obese diabetic mice. Mice administered intraperitoneally with FK-506 from 5 to 20weeks of age showed marked suppression of mononuclea