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Anti-tumor necrosis factor α switching in rheumatoid arthritis and juvenile chronic arthritis

✍ Scribed by Favalli, Ennio Giulio ;Arreghini, Marco ;Arnoldi, Cristina ;Panni, Benedetta ;Marchesoni, Antonio ;Tosi, Sergio ;Pontikaki, Irene

Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
112 KB
Volume
51
Category
Article
ISSN
0004-3591

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✦ Synopsis

COPD ϭ chronic obstructive pulmonary disease. 300 Letters * RA ϭ rheumatoid arthritis; JRA ϭ juvenile rheumatoid arthritis; ESR ϭ erythrocyte sedimentation rate; CRP ϭ C-reactive protein; VAS ϭ visual analog scale; GH ϭ general health; DAS28 ϭ Disease Activity Score in 28 joints; HAQ ϭ Health Assessment Questionnaire. † P Ͻ 0.05, RA versus JRA, by Wilcoxon's rank test for all comparisons.

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## Abstract ## Objective Treatment of rheumatoid arthritis (RA) with tumor necrosis factor (TNF)–blocking agents, including etanercept and infliximab, has resulted in reductions in the radiographic progression of RA. However, the exact mechanism by which this protection occurs has not been determi