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Anti-tumor activity of the HSP90 inhibitor SNX-2112 in pediatric cancer cell lines

โœ Scribed by Danielle C. Chinn; William S. Holland; Janet M. Yoon; Theodore Zwerdling; Philip C. Mack


Book ID
112167908
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
408 KB
Volume
58
Category
Article
ISSN
1545-5009

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## Abstract Drugs that inhibit the function of heat shock protein 90 (Hsp90) are of interest in the treatment of pediatric cancers because these agents deplete the cellular levels of signaling molecules that are important for the growth and survival of many childhood tumors. To generate preclinical