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Anti-tumor activity of noble indirubin derivatives in human solid tumor modelsIn Vitro

โœ Scribed by Soo-Hyun Kim; Soo Jeong Choi; Yong-Chul Kim; Hyo-Jeong Kuh


Book ID
107642077
Publisher
Springer
Year
2009
Tongue
English
Weight
443 KB
Volume
32
Category
Article
ISSN
0253-6269

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Cultured tumor cell lines, tumor xenografts grown in athymic nude mice, and a murine experimental metastasis model were used to assess the in vitro and in vivo anti-tumor activity of the potent IMP dehydrogenase (IMPDH) inhibitor, mycophenolic acid (MPA), and its morpholinoethyl ester pro-drug, myco