Anti-topoisomerase I autoantibodies in systemic sclerosis
✍ Scribed by Tamás Czömpöly; Diána Simon; László Czirják; Péter Németh
- Book ID
- 113482165
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 217 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1568-9972
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## Abstract ## Objective Fibroblasts play a crucial role in the development of systemic sclerosis (SSc), and antifibroblast antibodies (AFAs) capable of inducing a proinflammatory phenotype in fibroblasts have been detected in the sera of SSc patients. This study examined the prevalence of AFAs in
A Report of Two Cases MASATAKA KUWANA, TAKA0 FUJII, TSUNEYO MIMORI, and JUNICHI KABURAKI Anti-DNA topoisomerase I (anti-topo I) antibody profiles were compared before and after lung cancer in 2 patients with systemic sclerosis (SSc). Both patients developed adenocarcinoma of the lung late in the cou