Anti-TNF treatment of ulcerative colitis associated with idiopathic thrombocytopenic purpura
โ Scribed by W.G.N. Mares; J. Gerver; A.A.M. Masclee; M. Pierik
- Publisher
- John Wiley and Sons
- Year
- 2011
- Tongue
- English
- Weight
- 102 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1078-0998
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Idiopathic thrombocytopenic purpura (ITP) is refractory to initial treatment (steroids and splenectomy) in 25 to 30% of patients. These patients have a significant risk of fatal hemorrhage. Two patients with ITP refractory to multiple interventions and severe depression of platelet counts responded
## Abstract Chronic idiopathic thrombocytopenic purpura (ITP) is most often treated successfully with steroids and/or splenectomy. In those who fail to respond with the foregoing treatment, immunosuppressive drugs are sometimes added to the regimen. Cyclophosphamide has been reported heretofore to
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